Soft Gelatin Capsules
Soft gelatin capsules, or softgels, are an innovative drug delivery system known for their ability to encapsulate liquid or semi-liquid formulations. These capsules offer unique advantages in terms of bioavailability and patient compliance.
Structure and Production
Softgels are made of a single piece of gelatin shell that is soft and pliable. They typically contain plasticizers, such as glycerin or sorbitol, to maintain flexibility. The manufacturing process integrates the filling and sealing of the capsule in one step, ensuring precision and sterility.
Benefits
- Improved Bioavailability: Softgels enhance the absorption of poorly soluble drugs.
- Ease of Administration: Their smooth texture and palatability make them highly preferred by patients.
- Stability for Liquids: Encapsulating oils, vitamins, or other liquids protects the contents from oxidation and environmental damage.
Use Cases
Softgels are commonly used for nutritional supplements (like fish oil and vitamins) and liquid pharmaceuticals, offering a convenient and effective delivery system.